1ygk

X-ray diffraction
2.6Å resolution

Crystal Structure of Pyridoxal Kinase in Complex with Roscovitine and Derivatives

Released:
Source organism: Ovis aries
Entry authors: Tang L, Li M-H, Cao P, Wang F, Chang W-R, Bach S, Reinhardt J, Ferandin Y, Koken M, Galons H, Wan Y, Gray N, Meijer L, Jiang T, Liang D-C

Function and Biology Details

Reaction catalysed:
ATP + pyridoxal = ADP + pyridoxal 5'-phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pyridoxal kinase Chain: A
Molecule details ›
Chain: A
Length: 312 amino acids
Theoretical weight: 34.86 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: P82197 (Residues: 1-312; Coverage: 100%)
Gene names: PDXK, PKH
Sequence domains: Phosphomethylpyrimidine kinase
Structure domains: UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BSRF BEAMLINE 3W1A
Spacegroup: P3121
Unit cell:
a: 102.832Å b: 102.832Å c: 58.552Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.235 0.235 0.271