1yf4

X-ray diffraction
1.98Å resolution

Crystal Structure of trypsin-vasopressin complex

Released:
Source organism: Sus scrofa

Function and Biology Details

Reaction catalysed:
Preferential cleavage: Arg-|-, Lys-|-.
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Trypsin Chain: A
Molecule details ›
Chain: A
Length: 223 amino acids
Theoretical weight: 23.49 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P00761 (Residues: 9-231; Coverage: 97%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Vasopressin Chain: B
Molecule details ›
Chain: B
Length: 10 amino acids
Theoretical weight: 1.09 KDa
Source organism: Sus scrofa
Expression system: Not provided

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS
Spacegroup: P212121
Unit cell:
a: 59.274Å b: 61.953Å c: 69.146Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.185 0.226
Expression system: Not provided