X-ray diffraction
2.2Å resolution

Crystal structure of the G16S/N17T/P19A/S20A/N67D Variant Of Bovine seminal Ribonuclease


Function and Biology Details

Reaction catalysed:
(1a) an (RNA) containing cytidine = an (RNA)-3'-cytidine-2',3'-cyclophosphate + a 5'-hydroxy-ribonucleotide-3'-(RNA)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Seminal ribonuclease Chains: A, B
Molecule details ›
Chains: A, B
Length: 124 amino acids
Theoretical weight: 13.61 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
  • Canonical: P00669 (Residues: 27-150; Coverage: 100%)
Gene name: SRN
Structure domains: Ribonuclease A-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS
Spacegroup: P212121
Unit cell:
a: 48.959Å b: 61.102Å c: 81.215Å
α: 90° β: 90° γ: 90°
R R work R free
0.247 0.208 0.259
Expression system: Escherichia coli