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Dianhydrosugar-based benzamidine, factor Xa specific inhibitor in complex with bovine trypsin mutant

X-ray diffraction
1.4Å resolution
PDB entry 1y5a coloured by chain, front view.
PDB entry 1y5a coloured by chain, side view.
PDB entry 1y5a coloured by chain, top view.
Source organism: Bos taurus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Serine protease 1
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-133319

Macromolecules

Serine protease 1
Chain: T
Length: 223 amino acids
Theoretical weight: 23.39 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P00760 (Residues: 24-246; Coverage: 97%)
Gene names: PRSS1, TRP1, TRY1, TRYP1
Pfam: Trypsin
InterPro:
CATH: Trypsin-like serine proteases
Serine protease 1 in PDB entry 1y5a, assembly 1, front view.
Serine protease 1 in PDB entry 1y5a, assembly 1, side view.
Serine protease 1 in PDB entry 1y5a, assembly 1, top view.
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