1y4e

Solution NMR

NMR structure of transmembrane segment IV of the NHE1 isoform of the Na+/H+ exchanger

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sodium/hydrogen exchanger 1 Chain: A
Molecule details ›
Chain: A
Length: 27 amino acids
Theoretical weight: 3.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P19634 (Residues: 155-180; Coverage: 3%)
Gene names: APNH1, NHE1, SLC9A1

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 61%
Refinement method: simulated annealing
Chemical shifts: BMR6446  
Expression system: Escherichia coli