1wz9

X-ray diffraction
2.1Å resolution

The 2.1 A structure of a tumour suppressing serpin

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serpin B5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 375 amino acids
Theoretical weight: 42.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P36952 (Residues: 1-375; Coverage: 100%)
Gene names: PI5, SERPINB5
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 54.115Å b: 95.047Å c: 139.225Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.205 0.249
Expression system: Escherichia coli BL21