PDBe 1wyr

Solution NMR

Solution structure of the CH domain of human Rho guanine nucleotide exchange factor 6

Released:
Source organism: Homo sapiens
Entry authors: Tomizawa T, Kigawa T, Koshiba S, Inoue M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rho guanine nucleotide exchange factor 6 Chain: A
Molecule details ›
Chain: A
Length: 121 amino acids
Theoretical weight: 12.95 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q15052 (Residues: 4-111; Coverage: 14%)
Gene names: ARHGEF6, COOL2, KIAA0006, PIXA
Structure domains: Calponin-like domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 95%
Refinement method: torsion angle dynamics, restrainted molecular dynamics
Chemical shifts: BMR11129  
Expression system: Not provided