1wwt

Solution NMR

Solution structure of the TGS domain from human threonyl-tRNA synthetase

Released:
Source organism: Homo sapiens
Entry authors: Chikayama E, Kigawa T, Tomizawa T, Koshiba S, Inoue M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed:
ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Threonine--tRNA ligase 1, cytoplasmic Chain: A
Molecule details ›
Chain: A
Length: 88 amino acids
Theoretical weight: 9.37 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P26639 (Residues: 79-153; Coverage: 10%)
Gene names: TARS, TARS1
Sequence domains: TGS domain
Structure domains: Ubiquitin-like (UB roll)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, restrainted molecular dynamics
Expression system: Not provided