1wer

X-ray diffraction
1.6Å resolution

RAS-GTPASE-ACTIVATING DOMAIN OF HUMAN P120GAP

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras GTPase-activating protein 1 Chain: A
Molecule details ›
Chain: A
Length: 334 amino acids
Theoretical weight: 38.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P20936 (Residues: 714-1047; Coverage: 32%)
Gene names: GAP, RASA, RASA1
Sequence domains: GTPase-activator protein for Ras-like GTPase
Structure domains: GTPase Activation - p120gap; domain 1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID2
Spacegroup: P212121
Unit cell:
a: 42.2Å b: 55.6Å c: 142.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.221 0.271
Expression system: Escherichia coli