› 1wa9

X-ray diffraction
3.15Å resolution

Crystal Structure of the PAS repeat region of the Drosophila clock protein PERIOD

Released:
DOI: 10.2210/pdb1wa9/pdb
PDB 1wa9 coloured by chain and viewed from the front.
PDB 1wa9 coloured by chain and viewed from the side.
PDB 1wa9 coloured by chain and viewed from the top.
Source organism: Drosophila melanogaster
Primary publication:
Crystal structure and interactions of the PAS repeat region of the Drosophila clock protein PERIOD.
Yildiz O, Doi M, Yujnovsky I, Cardone L, Berndt A, Hennig S, Schulze S, Urbanke C, Sassone-Corsi P, Wolf E
Mol. Cell 17 69-82 (2005)
PMID: 15629718

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Period circadian protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 368 amino acids
Theoretical weight: 41.46 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P07663 (Residues: 232-599; Coverage: 30%)
Gene names: CG2647, per
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P43
Unit cell:
a: 140.44Å b: 140.44Å c: 61.45Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.228 0.277
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

16 review citations

Circadian Oscillators: Around the Transcription-Translation Feedback Loop and on to Output.
Hurley et al. (2016)
15 more

16 mentions without citation

Circadian oscillator proteins across the kingdoms of life: structural aspects.
Saini et al. (2019)
15 more