› 1w9r

Solution NMR

Solution Structure of Choline Binding Protein A, Domain R2, the Major Adhesin of Streptococcus pneumoniae

Released:
DOI: 10.2210/pdb1w9r/pdb
PDB entry 1w9r coloured by chain, ensemble of 19 models, front view.
PDB entry 1w9r coloured by chain, ensemble of 19 models, side view.
PDB entry 1w9r coloured by chain, ensemble of 19 models, top view.
Source organism: Streptococcus pneumoniae TIGR4
Primary publication:
Solution structure of choline binding protein A, the major adhesin of Streptococcus pneumoniae.
Luo R, Mann B, Lewis WS, Rowe A, Heath R, Stewart ML, Hamburger AE, Sivakolundu S, Lacy ER, Bjorkman PJ, Tuomanen E, Kriwacki RW
EMBO J 24 34-43 (2005)
PMID: 15616594

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-101493 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Choline binding protein A Chain: A
Molecule details ›
Chain: A
Length: 119 amino acids
Theoretical weight: 13.83 KDa
Source organism: Streptococcus pneumoniae TIGR4
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A0H2US50 (Residues: 326-443; Coverage: 17%)
Gene names: SP_2190, cbpA
Structure domains: choline binding protein A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: TAD
Expression system: Escherichia coli BL21(DE3)

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Citations

10 review citations

The polymeric immunoglobulin receptor: bridging innate and adaptive immune responses at mucosal surfaces.
Kaetzel CS. (2005)
9 more

4 mentions without citation

Choline Binding Proteins from Streptococcus pneumoniae: A Dual Role as Enzybiotics and Targets for the Design of New Antimicrobials.
Maestro et al. (2016)
3 more