Articles - 1w5r mentioned but not cited (1)
- Investigation of the catalytic triad of arylamine N-acetyltransferases: essential residues required for acetyl transfer to arylamines. Sandy J, Mushtaq A, Holton SJ, Schartau P, Noble ME, Sim E. Biochem J 390 115-123 (2005)
Reviews citing this publication (10)
- Arylamine N-acetyltransferases: structural and functional implications of polymorphisms. Sim E, Lack N, Wang CJ, Long H, Westwood I, Fullam E, Kawamura A. Toxicology 254 170-183 (2008)
- N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine. Hein DW. Expert Opin Drug Metab Toxicol 5 353-366 (2009)
- Arylamine N-acetyltransferases: from structure to function. Sim E, Walters K, Boukouvala S. Drug Metab. Rev. 40 479-510 (2008)
- Structure/function evaluations of single nucleotide polymorphisms in human N-acetyltransferase 2. Walraven JM, Zang Y, Trent JO, Hein DW. Curr. Drug Metab. 9 471-486 (2008)
- Arylamine N-acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery. Sim E, Abuhammad A, Ryan A. Br J Pharmacol 171 2705-2725 (2014)
- Arylamine N-acetyltransferases. Sim E, Westwood I, Fullam E. Expert Opin Drug Metab Toxicol 3 169-184 (2007)
- Arylamine N-acetyltransferases in mycobacteria. Sim E, Sandy J, Evangelopoulos D, Fullam E, Bhakta S, Westwood I, Krylova A, Lack N, Noble M. Curr. Drug Metab. 9 510-519 (2008)
- Update on the pharmacogenetics of NATs: structural considerations. Stanley LA, Sim E. Pharmacogenomics 9 1673-1693 (2008)
- Arylamine N-acetyltransferases: a structural perspective. Zhou X, Ma Z, Dong D, Wu B. Br. J. Pharmacol. 169 748-760 (2013)
- Crystal structure of arylamine N-acetyltransferases: insights into the mechanisms of action and substrate selectivity. Kubiak X, Dairou J, Dupret JM, Rodrigues-Lima F. Expert Opin Drug Metab Toxicol 9 349-362 (2013)
Articles citing this publication (24)
- Functional characterization of single-nucleotide polymorphisms and haplotypes of human N-acetyltransferase 2. Zang Y, Doll MA, Zhao S, States JC, Hein DW. Carcinogenesis 28 1665-1671 (2007)
- Divergence of cofactor recognition across evolution: coenzyme A binding in a prokaryotic arylamine N-acetyltransferase. Fullam E, Westwood IM, Anderton MC, Lowe ED, Sim E, Noble ME. J. Mol. Biol. 375 178-191 (2008)
- Kinetic and chemical mechanism of arylamine N-acetyltransferase from Mycobacterium tuberculosis. Sikora AL, Frankel BA, Blanchard JS. Biochemistry 47 10781-10789 (2008)
- Functional characterization of the A411T (L137F) and G364A (D122N) genetic polymorphisms in human N-acetyltransferase 2. Zang Y, Zhao S, Doll MA, States JC, Hein DW. Pharmacogenet Genomics 17 37-45 (2007)
- Reaction mechanism of azoreductases suggests convergent evolution with quinone oxidoreductases. Ryan A, Wang CJ, Laurieri N, Westwood I, Sim E. Protein Cell 1 780-790 (2010)
- Reversibly acetylated lysine residues play important roles in the enzymatic activity of Escherichia coli N-hydroxyarylamine O-acetyltransferase. Zhang QF, Gu J, Gong P, Wang XD, Tu S, Bi LJ, Yu ZN, Zhang ZP, Cui ZQ, Wei HP, Tao SC, Zhang XE, Deng JY. FEBS J. 280 1966-1979 (2013)
- Probing the architecture of the Mycobacterium marinum arylamine N-acetyltransferase active site. Abuhammad AM, Lowe ED, Fullam E, Noble M, Garman EF, Sim E. Protein Cell 1 384-392 (2010)
- Comparison of the Arylamine N-acetyltransferase from Mycobacterium marinum and Mycobacterium tuberculosis. Fullam E, Kawamura A, Wilkinson H, Abuhammad A, Westwood I, Sim E. Protein J. 28 281-293 (2009)
- Kinetic characterisation of arylamine N-acetyltransferase from Pseudomonas aeruginosa. Westwood IM, Sim E. BMC Biochem. 8 3 (2007)
- Functional and structural characterization of the arylamine N-acetyltransferase from the opportunistic pathogen Nocardia farcinica. Martins M, Pluvinage B, Li de la Sierra-Gallay I, Barbault F, Dairou J, Dupret JM, Rodrigues-Lima F. J. Mol. Biol. 383 549-560 (2008)
- Understanding Protein Palmitoylation: Biological Significance and Enzymology. Guan X, Fierke CA. 54 1888-1897 (2011)
- Interaction of wild type, G68R and L125M isoforms of the arylamine-N-acetyltransferase from Mycobacterium tuberculosis with isoniazid: a computational study on a new possible mechanism of resistance. Ramos RM, Perez JM, Baptista LA, de Amorim HL. J Mol Model 18 4013-4024 (2012)
- Structural and biochemical characterization of an active arylamine N-acetyltransferase possessing a non-canonical Cys-His-Glu catalytic triad. Kubiak X, Li de la Sierra-Gallay I, Chaffotte AF, Pluvinage B, Weber P, Haouz A, Dupret JM, Rodrigues-Lima F. J. Biol. Chem. 288 22493-22505 (2013)
- The role of lysine(100) in the binding of acetylcoenzyme A to human arylamine N-acetyltransferase 1: implications for other acetyltransferases. Minchin RF, Butcher NJ. Biochem. Pharmacol. 94 195-202 (2015)
- Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190. Zhou X, Zhang N, Liu L, Walters KJ, Hanna PE, Wagner CR. FEBS J 276 6928-6941 (2009)
- A low-barrier hydrogen bond mediates antibiotic resistance in a noncanonical catalytic triad. Kumar P, Serpersu EH, Cuneo MJ. Sci Adv 4 eaas8667 (2018)
- Discovery of a previously unknown biosynthetic capacity of naringenin chalcone synthase by heterologous expression of a tomato gene cluster in yeast. Kong D, Li S, Smolke CD. Sci Adv 6 eabd1143 (2020)
- Mutational analysis and homology modelling of SyrC, the aminoacyltransferase in the biosynthesis of syringomycin. Fullone MR, Paiardini A, Gross DC, Lu SE, Fiore A, Grgurina I. Biochem. Biophys. Res. Commun. 364 201-207 (2007)
- NAT2 polymorphisms and their influence on the pharmacology and toxicity of isoniazid in TB patients. Werely CJ, Donald PR, van Helden PD. Per Med 4 123-131 (2007)
- The conserved glycine/alanine residue of the active-site loop containing the putative acetylCoA-binding motif is essential for the overall structural integrity of Mesorhizobium loti arylamine N-acetyltransferase 1. Atmane N, Dairou J, Flatters D, Martins M, Pluvinage B, Derreumaux P, Dupret JM, Rodrigues-Lima F. Biochem. Biophys. Res. Commun. 361 256-262 (2007)
- Biochemical Characterization of Arylamine N-acetyltransferases From Vibrio vulnificus. Liu X, Liu Y, Zhao G, Zhang Y, Liu L, Wang J, Wang Y, Zhang S, Li X, Guo D, Wang P, Xu X. Front Microbiol 11 595083 (2020)
- Comparative Investigation of 15 Xenobiotic-Metabolizing N-Acetyltransferase (NAT) Homologs from Bacteria. Garefalaki V, Papavergi MG, Savvidou O, Papanikolaou G, Felföldi T, Márialigeti K, Fakis G, Boukouvala S. Appl Environ Microbiol 87 e0081921 (2021)
- PtmC Catalyzes the Final Step of Thioplatensimycin, Thioplatencin, and Thioplatensilin Biosynthesis and Expands the Scope of Arylamine N-Acetyltransferases. Zheng CJ, Kalkreuter E, Fan BY, Liu YC, Dong LB, Shen B. ACS Chem Biol 16 96-105 (2021)
- The actinobacterium Tsukamurella paurometabola has a functionally divergent arylamine N-acetyltransferase (NAT) homolog. Garefalaki V, Kontomina E, Ioannidis C, Savvidou O, Vagena-Pantoula C, Papavergi MG, Olbasalis I, Patriarcheas D, Fylaktakidou KC, Felföldi T, Márialigeti K, Fakis G, Boukouvala S. World J. Microbiol. Biotechnol. 35 174 (2019)