1w5r

X-ray diffraction
1.45Å resolution

X-ray crystallographic structure of a C70Q Mycobacterium smegmatis N- arylamine Acetyltransferase

Released:

Function and Biology Details

Reaction catalysed:
Acetyl-CoA + an arylamine = CoA + an N-acetylarylamine
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Arylamine N-acetyltransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 278 amino acids
Theoretical weight: 30.59 KDa
Source organism: Mycolicibacterium smegmatis
Expression system: Escherichia coli
UniProt:
  • Canonical: O86309 (Residues: 1-275; Coverage: 100%)
Gene name: nat
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P41212
Unit cell:
a: 98.884Å b: 98.884Å c: 130.815Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.196 0.22
Expression system: Escherichia coli