X-ray diffraction
1.8Å resolution

structure of the oxidised form of human thioredoxin 2


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Thioredoxin, mitochondrial Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 119 amino acids
Theoretical weight: 13.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q99757 (Residues: 60-166; Coverage: 65%)
Gene names: TRX2, TXN2
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: P1
Unit cell:
a: 49.06Å b: 49.14Å c: 78.71Å
α: 87.75° β: 82.77° γ: 79.2°
R R work R free
0.172 0.169 0.228
Expression system: Escherichia coli