Function and Biology Details
Reaction catalysed:
(1a) (2R,3S)-3-isopropylmalate + NAD(+) = (2S)-2-isopropyl-3-oxosuccinate + NADH
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
3-isopropylmalate dehydrogenase (preferred)
PDBe Complex ID:
PDB-CPX-161752 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-isopropylmalate dehydrogenase
Molecule details ›
Chains: A, B, C, D
Length: 337 amino acids
Theoretical weight: 35.44 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
Sequence domains: Isocitrate/isopropylmalate dehydrogenase
Structure domains: Isopropylmalate Dehydrogenase
Length: 337 amino acids
Theoretical weight: 35.44 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
- Canonical:
P9WKK9 (Residues: 2-336; Coverage: 100%)
Sequence domains: Isocitrate/isopropylmalate dehydrogenase
Structure domains: Isopropylmalate Dehydrogenase
