Assemblies
Assembly Name:
Cyclin A2-CDK2 complex
Multimeric state:
hetero dimer
Accessible surface area:
23681.9 Å2
Buried surface area:
3884.09 Å2
Dissociation area:
1,512.97
Å2
Dissociation energy (ΔGdiss):
9.78
kcal/mol
Dissociation entropy (TΔSdiss):
13.17
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-148886
Assembly Name:
Cyclin A2-CDK2 complex
Multimeric state:
hetero dimer
Accessible surface area:
23570.11 Å2
Buried surface area:
3893.85 Å2
Dissociation area:
1,508.07
Å2
Dissociation energy (ΔGdiss):
9.04
kcal/mol
Dissociation entropy (TΔSdiss):
13.14
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-148886
Macromolecules
Chains: A, C
Length: 309 amino acids
Theoretical weight: 35.25 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Pfam: Protein kinase domain
InterPro:
SCOP: Protein kinases, catalytic subunit
Length: 309 amino acids
Theoretical weight: 35.25 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P24941 (Residues: 1-298; Coverage: 100%)
Pfam: Protein kinase domain
InterPro:
- Protein kinase-like domain superfamily
- Protein kinase domain
- Protein kinase, ATP binding site
- Serine/threonine-protein kinase, active site
SCOP: Protein kinases, catalytic subunit
Chains: B, D
Length: 265 amino acids
Theoretical weight: 30.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Pfam:
InterPro:
SCOP: Cyclin
Length: 265 amino acids
Theoretical weight: 30.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P20248 (Residues: 169-432; Coverage: 61%)
Pfam:
InterPro:
- Cyclin A/B-like
- Cyclin-like superfamily
- Cyclin
- Cyclin, N-terminal
- Cyclin-like domain
- Cyclin, C-terminal domain
SCOP: Cyclin
