› 1vna

Solution NMR

PROTON NUCLEAR MAGNETIC RESONANCE AND DISTANCE GEOMETRY(SLASH)SIMULATED ANNEALING STUDIES ON THE VARIANT-1 NEUROTOXIN FROM THE NEW WORLD SCORPION CENTRUROIDES SCULPTURATUS EWING

Released:
DOI: 10.2210/pdb1vna/pdb
PDB entry 1vna coloured by chain, ensemble of 26 models, front view.
PDB entry 1vna coloured by chain, ensemble of 26 models, side view.
PDB entry 1vna coloured by chain, ensemble of 26 models, top view.
Source organism: Centruroides sculpturatus
Primary publication:
Proton nuclear magnetic resonance and distance geometry/simulated annealing studies on the variant-1 neurotoxin from the New World scorpion Centruroides sculpturatus Ewing.
Lee W, Jablonsky MJ, Watt DD, Krishna NR
Biochemistry 33 2468-75 (1994)
PMID: 8117707

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134329 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Toxin CsEv1 Chain: A
Molecule details ›
Chain: A
Length: 65 amino acids
Theoretical weight: 7.33 KDa
Source organism: Centruroides sculpturatus
Expression system: Not provided
UniProt:
  • Canonical: P01492 (Residues: 20-84; Coverage: 96%)
Sequence domains: Scorpion toxin-like domain
Structure domains: Knottin, scorpion toxin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

2 review citations

Scorpion toxins specific for Na+-channels.
Possani et al. (1999)
1 more

1 mention without citation

A new type of scorpion Na+-channel-toxin-like polypeptide active on K+ channels.
Srairi-Abid et al. (2005)