X-ray diffraction
1.55Å resolution

Crystal structure of 6-phosphogluconolactonase (TM1154) from Thermotoga maritima at 1.70A resolution

Source organism: Thermotoga maritima
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed:
6-phospho-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconate
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
6-phosphogluconolactonase Chain: A
Molecule details ›
Chain: A
Length: 232 amino acids
Theoretical weight: 26.82 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
  • Canonical: Q9X0N8 (Residues: 1-220; Coverage: 100%)
Gene names: TM_1154, devB, pgl
Sequence domains: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
Structure domains: Rossmann fold

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: C2221
Unit cell:
a: 37.733Å b: 75.146Å c: 148.443Å
α: 90° β: 90° γ: 90°
R R work R free
0.167 0.165 0.204
Expression system: Escherichia coli