1vgh

Solution NMR

HEPARIN-BINDING DOMAIN FROM VASCULAR ENDOTHELIAL GROWTH FACTOR, NMR, 20 STRUCTURES

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Vascular endothelial growth factor A Chain: A
Molecule details ›
Chain: A
Length: 55 amino acids
Theoretical weight: 6.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P15692 (Residues: 182-232; Coverage: 25%)
  • Best match: P15692-11 (Residues: 317-371)
Gene names: VEGF, VEGFA
Structure domains: Vascular endothelial growth factor, heparin-binding domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 54%
Refinement method: DISTANCE GEOMETRY/ SIMULATED ANNEALING/RESTRAINED MOLECULAR DYNAMICS
Expression system: Escherichia coli