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The crystal structure of prostaglandin F synthase from Trypanosoma brucei

Source organism: Trypanosoma brucei
Biochemical function: D-arabinose 1-dehydrogenase [NAD(P)+] activity
Biological process: small molecule metabolic process
Cellular component: cytoplasm

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GO terms

Sequence family

Pfam Protein family (Pfam)
PF00248
Domain description: Aldo/keto reductase family
Occurring in:
  1. 9,11-endoperoxide prostaglandin H2 reductase
The deposited structure of PDB entry 1vbj contains 2 copies of Pfam domain PF00248 (Aldo/keto reductase family) in 9,11-endoperoxide prostaglandin H2 reductase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR020471
Domain description: Aldo-keto reductase
Occurring in:
  1. 9,11-endoperoxide prostaglandin H2 reductase
IPR018170
Domain description: Aldo/keto reductase, conserved site
Occurring in:
  1. 9,11-endoperoxide prostaglandin H2 reductase
IPR036812
Domain description: NADP-dependent oxidoreductase domain superfamily
Occurring in:
  1. 9,11-endoperoxide prostaglandin H2 reductase
IPR023210
Domain description: NADP-dependent oxidoreductase domain
Occurring in:
  1. 9,11-endoperoxide prostaglandin H2 reductase
IPR044499
Domain description: Aldo-keto reductase family 5A
Occurring in:
  1. 9,11-endoperoxide prostaglandin H2 reductase

Structure domain

CATH CATH domain
3.20.20.100
Class: Alpha Beta
Architecture: Alpha-Beta Barrel
Topology: TIM Barrel
Homology: NADP-dependent oxidoreductase domain
Occurring in:
  1. 9,11-endoperoxide prostaglandin H2 reductase
The deposited structure of PDB entry 1vbj contains 2 copies of CATH domain 3.20.20.100 (TIM Barrel) in 9,11-endoperoxide prostaglandin H2 reductase. Showing 1 copy in chain A.

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