› 1vam

X-ray diffraction
2.75Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136271 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Concanavalin-A, 2nd part Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 237 amino acids
Theoretical weight: 25.62 KDa
Source organism: Canavalia ensiformis
UniProt:
  • Canonical: P02866 (Residues: 28-148; Coverage: 46%)
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments

3 bound ligands:
Ligand PNA 4 x PNA
Ligand MN 4 x MN
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21212
Unit cell:
a: 135.19Å b: 155.38Å c: 71.25Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.185 0.26

Quick links

Citations

2 review citations

Immune mechanisms of Concanavalin A model of autoimmune hepatitis.
Wang et al. (2012)
1 more

2 mentions without citation

Overview of the Structure⁻Function Relationships of Mannose-Specific Lectins from Plants, Algae and Fungi.
Barre et al. (2019)
1 more