1v8k

X-ray diffraction
2.25Å resolution

The Crystal Structure of the Minimal Functional Domain of the Microtubule Destabilizer KIF2C Complexed with Mg-AMPPNP

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinesin-like protein KIF2C Chain: A
Molecule details ›
Chain: A
Length: 410 amino acids
Theoretical weight: 46.8 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q922S8 (Residues: 183-585; Coverage: 56%)
Gene name: Kif2c
Structure domains: Kinesin motor domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: C222
Unit cell:
a: 61.068Å b: 191.475Å c: 74.627Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.238 0.215 0.252
Expression system: Escherichia coli