X-ray diffraction
2Å resolution

Crystal structure of Phosphoribosyl anthranilate isomerase from Thermus Thermophilus


Function and Biology Details

Reaction catalysed:
N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
N-(5'-phosphoribosyl)anthranilate isomerase Chains: A, B
Molecule details ›
Chains: A, B
Length: 203 amino acids
Theoretical weight: 21.98 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli
  • Canonical: P83825 (Residues: 1-203; Coverage: 100%)
Gene name: trpF
Sequence domains: N-(5'phosphoribosyl)anthranilate (PRA) isomerase
Structure domains: Aldolase class I

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: P4132
Unit cell:
a: 144.205Å b: 144.205Å c: 144.205Å
α: 90° β: 90° γ: 90°
R R work R free
0.264 0.262 0.296
Expression system: Escherichia coli