1v0d

X-ray diffraction
2.6Å resolution

Crystal Structure of Caspase-activated DNase (CAD)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA fragmentation factor subunit beta Chain: A
Molecule details ›
Chain: A
Length: 329 amino acids
Theoretical weight: 37.6 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O54788 (Residues: 1-329; Coverage: 96%)
Gene names: Cad, Dffb
Structure domains: Helix Hairpins

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P64
Unit cell:
a: 110.189Å b: 110.189Å c: 73.982Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.218 0.218 0.246
Expression system: Escherichia coli BL21(DE3)