1v05

X-ray diffraction
1.43Å resolution

Dimerization of human Filamin C: crystal structure of the domain 24

Released:
Source organism: Homo sapiens
Primary publication:
Structural basis for vertebrate filamin dimerization.
Structure 13 111-9 (2005)
PMID: 15642266

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Filamin-C Chain: A
Molecule details ›
Chain: A
Length: 96 amino acids
Theoretical weight: 10.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14315 (Residues: 2631-2725; Coverage: 4%)
Gene names: ABPL, FLN2, FLNC
Sequence domains: Filamin/ABP280 repeat
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X13
Spacegroup: P6122
Unit cell:
a: 48.099Å b: 48.099Å c: 117.485Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.188 0.186 0.205
Expression system: Escherichia coli