X-ray diffraction
2.4Å resolution

Structure of acetylcholinesterase (E.C. complexed with N-9-(1',2',3',4'-Tetrahydroacridinyl)-1,8- diaminooctane at 2.4 angstroms resolution.


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Acetylcholinesterase Chain: A
Molecule details ›
Chain: A
Length: 537 amino acids
Theoretical weight: 60.79 KDa
Source organism: Tetronarce californica
  • Canonical: P04058 (Residues: 22-556; Coverage: 95%)
  • Best match: P04058-2 (Residues: 22-558)
Gene name: ache
Sequence domains: Carboxylesterase family
Structure domains: Rossmann fold

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P3121
Unit cell:
a: 111.193Å b: 111.193Å c: 136.853Å
α: 90° β: 90° γ: 120°
R R work R free
0.194 0.194 0.24