PDBe 1upk

X-ray diffraction
1.85Å resolution

Crystal structure of MO25 in complex with a C-terminal peptide of STRAD


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calcium-binding protein 39 Chain: A
Molecule details ›
Chain: A
Length: 341 amino acids
Theoretical weight: 40.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9Y376 (Residues: 1-341; Coverage: 100%)
Gene names: CAB39, CGI-66, MO25
Sequence domains: Mo25-like
Structure domains: Leucine-rich Repeat Variant
STE20-related kinase adapter protein alpha Chain: B
Molecule details ›
Chain: B
Length: 12 amino acids
Theoretical weight: 1.54 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: Q7RTN6 (Residues: 420-431; Coverage: 3%)
Gene names: LYK5, STRAD, STRADA

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P21212
Unit cell:
a: 77.65Å b: 134.033Å c: 40.224Å
α: 90° β: 90° γ: 90°
R R work R free
0.202 0.202 0.23
Expression systems:
  • Escherichia coli
  • Not provided