X-ray diffraction
1.79Å resolution

Crystal structure of an acidic, non-myotoxic phospholipase A2 from the venom of Bothrops jararacussu


Function and Biology Details

Reaction catalysed:
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Acidic phospholipase A2 BthA-1 Chain: X
Molecule details ›
Chain: X
Length: 122 amino acids
Theoretical weight: 13.7 KDa
Source organism: Bothrops jararacussu
  • Canonical: Q8AXY1 (Residues: 17-138; Coverage: 100%)
Sequence domains: Phospholipase A2
Structure domains: Phospholipase A2 domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LNLS BEAMLINE D03B-MX1
Spacegroup: C2221
Unit cell:
a: 39.99Å b: 53.99Å c: 90.46Å
α: 90° β: 90° γ: 90°
R R work R free
0.164 0.161 0.229