PDBe 1um0

X-ray diffraction
1.95Å resolution

Crystal structure of chorismate synthase complexed with FMN

Released:

Function and Biology Details

Reaction catalysed:
5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chorismate synthase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 365 amino acids
Theoretical weight: 40.15 KDa
Source organism: Helicobacter pylori
Expression system: Escherichia coli
UniProt:
  • Canonical: P56122 (Residues: 1-365; Coverage: 100%)
Gene name: aroC
Sequence domains: Chorismate synthase
Structure domains: Chorismate synthase AroC

Ligands and Environments


Cofactor: Ligand FMN 4 x FMN
No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 6B
Spacegroup: I4
Unit cell:
a: 146.686Å b: 146.686Å c: 132.31Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.214 0.243
Expression system: Escherichia coli