X-ray diffraction
2.2Å resolution

CGL2 in complex with Thomsen-Friedenreich antigen

Source organism: Coprinopsis cinerea

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Galectin-2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 150 amino acids
Theoretical weight: 16.77 KDa
Source organism: Coprinopsis cinerea
Expression system: Saccharomyces cerevisiae
  • Canonical: Q9P4R8 (Residues: 1-150; Coverage: 100%)
Gene name: Cgl2
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: NGA, GAL
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P21
Unit cell:
a: 44.137Å b: 113.634Å c: 65.091Å
α: 90° β: 108.48° γ: 90°
R R work R free
0.219 0.219 0.299
Expression system: Saccharomyces cerevisiae