Solution NMR

NMR structure of the R3H domain from Poly(A)-specific Ribonuclease

Source organism: Mus musculus
Entry authors: Nagata T, Muto Y, Hayami N, Uda H, Shirouzu M, Terada T, Kigawa T, Inoue M, Yabuki T, Aoki M, Seki E, Matsuda T, Hirota H, Yoshida M, Kobayashi N, Tanaka A, Osanai T, Matsuo Y, Arakawa T, Carninci P, Kawai J, Hayashizaki Y, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed:
Exonucleolytic cleavage of poly(A) to 5'-AMP
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Poly(A)-specific ribonuclease PARN Chain: A
Molecule details ›
Chain: A
Length: 87 amino acids
Theoretical weight: 9.94 KDa
Source organism: Mus musculus
Expression system: Not provided
  • Canonical: Q8VDG3 (Residues: 169-242; Coverage: 12%)
Gene name: Parn
Structure domains: R3H-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, simulated annealing
Expression system: Not provided