1ua4

X-ray diffraction
1.9Å resolution

Crystal Structure of an ADP-dependent Glucokinase from Pyrococcus furiosus

Released:

Function and Biology Details

Reaction catalysed:
ADP + D-glucosamine = AMP + D-glucosamine 6-phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADP-dependent glucose/glucosamine kinase Chain: A
Molecule details ›
Chain: A
Length: 455 amino acids
Theoretical weight: 51.33 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9V2Z6 (Residues: 1-455; Coverage: 100%)
Gene names: PF0312, glkA
Sequence domains: ADP-specific Phosphofructokinase/Glucokinase conserved region
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: I222
Unit cell:
a: 112.677Å b: 88.948Å c: 103.355Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.168 0.168 0.205
Expression system: Escherichia coli