PDBe 1u7b

X-ray diffraction
1.88Å resolution

Crystal structure of hPCNA bound to residues 331-350 of the flap endonuclease-1 (FEN1)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Proliferating cell nuclear antigen Chain: A
Molecule details ›
Chain: A
Length: 261 amino acids
Theoretical weight: 28.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12004 (Residues: 1-261; Coverage: 100%)
Gene name: PCNA
Sequence domains:
Structure domains: Proliferating Cell Nuclear Antigen
Flap endonuclease 1 Chain: B
Molecule details ›
Chain: B
Length: 20 amino acids
Theoretical weight: 2.2 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P39748 (Residues: 331-350; Coverage: 5%)
Gene names: FEN1, RAD2

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P63
Unit cell:
a: 81.498Å b: 81.498Å c: 67.312Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.217 0.217 0.265
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided