X-ray diffraction
1.85Å resolution

Crystal structure of the Kelch domain of human Keap1

Source organism: Homo sapiens
Primary publication:
Crystal structure of the Kelch domain of human Keap1.
J. Biol. Chem. 279 54750-8 (2004)
PMID: 15475350

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Kelch-like ECH-associated protein 1 Chain: X
Molecule details ›
Chain: X
Length: 308 amino acids
Theoretical weight: 33.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q14145 (Residues: 321-609; Coverage: 46%)
Gene names: INRF2, KEAP1, KIAA0132, KLHL19
Sequence domains: Kelch motif
Structure domains: Kelch-type beta propeller

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P6522
Unit cell:
a: 85.892Å b: 85.892Å c: 148.753Å
α: 90° β: 90° γ: 120°
R R work R free
0.149 0.148 0.182
Expression system: Escherichia coli