1u53

X-ray diffraction
1.56Å resolution

Novel X-Ray Structure of Na-ASP-2, a PR-1 protein from the nematode parasite Necator americanus and a vaccine antigen for human hookworm infection

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SCP domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 196 amino acids
Theoretical weight: 21.21 KDa
Source organism: Necator americanus
Expression system: Komagataella pastoris
UniProt:
  • Canonical: Q7Z1H1 (Residues: 15-210; Coverage: 100%)
Gene name: ASP2
Structure domains: CAP

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P21
Unit cell:
a: 37.89Å b: 51.54Å c: 43.63Å
α: 90° β: 114.06° γ: 90°
R-values:
R R work R free
0.178 0.175 0.224
Expression system: Komagataella pastoris