1u4f

X-ray diffraction
2.41Å resolution

Crystal Structure of Cytoplasmic Domains of IRK1 (Kir2.1) channel

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo tetramer (preferred)
homo octamer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inward rectifier potassium channel 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 270 amino acids
Theoretical weight: 30.84 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P35561 (Residues: 187-428; Coverage: 57%)
Gene names: Irk1, Kcnj2
Sequence domains: Inward rectifier potassium channel C-terminal domain
Structure domains: G protein-activated inward rectifier potassium channel 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: C2221
Unit cell:
a: 112.461Å b: 138.294Å c: 138.745Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 0.225 0.281
Expression system: Escherichia coli BL21(DE3)