1u4e

X-ray diffraction
2.09Å resolution

Crystal Structure of Cytoplasmic Domains of GIRK1 channel

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
G protein-activated inward rectifier potassium channel 1 Chain: A
Molecule details ›
Chain: A
Length: 212 amino acids
Theoretical weight: 24.15 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P63250 (Residues: 188-371; Coverage: 37%)
Gene names: Girk1, Kcnj3
Sequence domains: Inward rectifier potassium channel C-terminal domain
Structure domains: G protein-activated inward rectifier potassium channel 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: P4212
Unit cell:
a: 76.357Å b: 76.357Å c: 92.164Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.194 0.235
Expression system: Escherichia coli BL21(DE3)