X-ray diffraction
1.89Å resolution

Crystal structure of WLAC mutant of dimerisation domain of NF-kB p50 transcription factor


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Nuclear factor NF-kappa-B p50 subunit Chain: A
Molecule details ›
Chain: A
Length: 106 amino acids
Theoretical weight: 12.28 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P25799 (Residues: 245-350; Coverage: 11%)
Gene name: Nfkb1
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.2
Spacegroup: P41212
Unit cell:
a: 63.087Å b: 63.087Å c: 65.279Å
α: 90° β: 90° γ: 90°
R R work R free
0.187 0.185 0.22
Expression system: Escherichia coli BL21(DE3)