1u0r

X-ray diffraction
2.8Å resolution

Crystal structure of Mycobacterium tuberculosis NAD kinase

Released:

Function and Biology Details

Reaction catalysed:
ATP + NAD(+) = ADP + NADP(+)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NAD kinase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 307 amino acids
Theoretical weight: 32.94 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WHV7 (Residues: 1-307; Coverage: 100%)
Gene names: MTCI125.17, Rv1695, ppnK
Sequence domains: ATP-NAD kinase N-terminal domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P43212
Unit cell:
a: 118.51Å b: 118.51Å c: 222.3Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.223 0.286
Expression system: Escherichia coli