X-ray diffraction
2Å resolution

Crystal structure of the streptococcal pyrogenic exotoxin J (SPE-J)


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Exotoxin J Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 211 amino acids
Theoretical weight: 24.8 KDa
Source organism: Streptococcus pyogenes
Expression system: Escherichia coli
  • Canonical: Q7BAE3 (Residues: 22-232; Coverage: 91%)
Gene name: speJ
Sequence domains: Staphylococcal/Streptococcal toxin, beta-grasp domain
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: C2
Unit cell:
a: 167.33Å b: 46.33Å c: 72.22Å
α: 90° β: 90.54° γ: 90°
R R work R free
0.231 0.218 0.249
Expression system: Escherichia coli