1tx6

X-ray diffraction
2.2Å resolution

trypsin:BBI complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
Non-polymer only trimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Trypsin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 223 amino acids
Theoretical weight: 23.49 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P00761 (Residues: 9-231; Coverage: 97%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Bowman-Birk type trypsin inhibitor Chains: I, J
Molecule details ›
Chains: I, J
Length: 125 amino acids
Theoretical weight: 13.93 KDa
Source organism: Hordeum vulgare
UniProt:
  • Canonical: P12940 (Residues: 1-41, 42-124; Coverage: 100%)
Gene name: BBBI
Sequence domains: Bowman-Birk serine protease inhibitor family
Structure domains: Cysteine Protease (Bromelain) Inhibitor, subunit H

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: P212121
Unit cell:
a: 67.208Å b: 88.539Å c: 203.89Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.223 0.223 0.274