› 1twl

X-ray diffraction
2.2Å resolution

Inorganic pyrophosphatase from Pyrococcus furiosus Pfu-264096-001

Released:
DOI: 10.2210/pdb1twl/pdb
PDB 1twl coloured by chain and viewed from the front.
PDB 1twl coloured by chain and viewed from the side.
PDB 1twl coloured by chain and viewed from the top.
Source organism: Pyrococcus furiosus
Entry authors: Zhou W, Tempel W, Liu Z-J, Chen L, Clancy Kelley L-L, Dillard BD, Hopkins RC, Arendall III WB, Rose JP, Eneh JC, Hopkins RC, Jenney Jr FE, Lee HS, Li T, Poole II FL, Shah C, Sugar FJ, Adams MWW, Richardson JS, Richardson DC, Wang B-C, Southeast Collaboratory for Structural Genomics (SECSG)

Function and Biology Details

Reaction catalysed: 
Diphosphate + H(2)O = 2 phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo hexamer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inorganic pyrophosphatase Chain: A
Molecule details ›
Chain: A
Length: 186 amino acids
Theoretical weight: 21.86 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8U438 (Residues: 2-178; Coverage: 99%)
Gene names: PF0257, ppa
Sequence domains: Inorganic pyrophosphatase
Structure domains: Inorganic pyrophosphatase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: R32
Unit cell:
a: 113.434Å b: 113.434Å c: 73.313Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.197 0.194 0.257
Expression system: Escherichia coli

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