› 1tr9

X-ray diffraction
1.8Å resolution

Structure of beta-hexosaminidase from Vibrio cholerae

Released:
DOI: 10.2210/pdb1tr9/pdb
PDB entry 1tr9 coloured by chain, front view.
PDB entry 1tr9 coloured by chain, side view.
PDB entry 1tr9 coloured by chain, top view.
Source organism: Vibrio cholerae
Entry authors: Gorman J, Shapiro L, Burley SK, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed: 
Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192108 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-hexosaminidase Chain: A
Molecule details ›
Chain: A
Length: 341 amino acids
Theoretical weight: 38.3 KDa
Source organism: Vibrio cholerae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9KU37 (Residues: 2-330; Coverage: 100%)
Gene names: VC_0692, nagZ
Sequence domains: Glycosyl hydrolase family 3 N terminal domain
Structure domains: Glycoside hydrolase, family 3, N-terminal domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P212121
Unit cell:
a: 48.98Å b: 79.378Å c: 86.685Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.172 0.17 0.203
Expression system: Escherichia coli BL21(DE3)

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