1tks

X-ray diffraction
1.6Å resolution

Crystal structure of 3,4-Dihydroxy-2-butanone 4-phosphate Synthase of Candida albicans

Released:

Function and Biology Details

Reaction catalysed:
D-ribulose 5-phosphate = formate + L-3,4-dihydroxybutan-2-one 4-phosphate
Biochemical function:
Biological process:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3,4-dihydroxy-2-butanone 4-phosphate synthase Chains: A, B
Molecule details ›
Chains: A, B
Length: 204 amino acids
Theoretical weight: 22.68 KDa
Source organism: Candida albicans SC5314
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5A3V6 (Residues: 1-204; Coverage: 100%)
Gene names: CAALFM_C112360CA, CaO19.12693, CaO19.5228, RIB3
Sequence domains: 3,4-dihydroxy-2-butanone 4-phosphate synthase
Structure domains: DHBP synthase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P1
Unit cell:
a: 40.439Å b: 48.134Å c: 59.804Å
α: 66.229° β: 71.979° γ: 89.856°
R-values:
R R work R free
0.192 0.192 0.219
Expression system: Escherichia coli