› 1tkf

X-ray diffraction
1.2Å resolution

Streptomyces griseus aminopeptidase complexed with D-tryptophan

Released:
DOI: 10.2210/pdb1tkf/pdb
PDB 1tkf coloured by chain and viewed from the front.
PDB 1tkf coloured by chain and viewed from the side.
PDB 1tkf coloured by chain and viewed from the top.
Source organism: Streptomyces griseus
Entry authors: Reiland V, Gilboa R, Spungin-Bialik A, Schomburg D, Shoham Y, Blumberg S, Shoham G

Function and Biology Details

Reaction catalysed: 
Release of an N-terminal amino acid with a preference for large hydrophobic amino-terminus residues
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aminopeptidase S Chain: A
Molecule details ›
Chain: A
Length: 284 amino acids
Theoretical weight: 29.75 KDa
Source organism: Streptomyces griseus
UniProt:
  • Canonical: P80561 (Residues: 46-329; Coverage: 71%)
Gene name: SGR_5809
Structure domains: Zn peptidases

Ligands and Environments

3 bound ligands:
Ligand ZN 2 x ZN
Ligand CA 1 x CA
Ligand DTR 1 x DTR
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P41212
Unit cell:
a: 60.606Å b: 60.606Å c: 144.186Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.13 0.13 0.168

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