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X-ray diffraction
2Å resolution

Human GM2 Activator Protein PAF complex

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric
homo trimer
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ganglioside GM2 activator Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 164 amino acids
Theoretical weight: 17.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P17900 (Residues: 32-193; Coverage: 95%)
Gene name: GM2A
Sequence domains: ML domain
Structure domains: Ganglioside GM2 activator

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P212121
Unit cell:
a: 63.47Å b: 86.51Å c: 120.47Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.189 0.234
Expression system: Escherichia coli BL21(DE3)