1t6c

X-ray diffraction
1.53Å resolution

Structural characterization of the Ppx/GppA protein family: crystal structure of the Aquifex aeolicus family member

Released:

Function and Biology Details

Reactions catalysed:
(Polyphosphate)(n) + H(2)O = (polyphosphate)(n-1) + phosphate
Guanosine 5'-triphosphate,3'-diphosphate + H(2)O = guanosine 3',5'-bis(diphosphate) + phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ppx-GppA domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 315 amino acids
Theoretical weight: 35.83 KDa
Source organism: Aquifex aeolicus VF5
Expression system: Escherichia coli
UniProt:
  • Canonical: O67040 (Residues: 1-312; Coverage: 100%)
Gene names: aq_891, ppx
Sequence domains: Ppx/GppA phosphatase family
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I711
Spacegroup: P212121
Unit cell:
a: 50.776Å b: 70.287Å c: 90.783Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.162 0.162 0.217
Expression system: Escherichia coli