X-ray diffraction
2.5Å resolution

Crystal structure of B. anthracis Protective Antigen complexed with human Anthrax toxin receptor


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protective antigen Chain: X
Anthrax toxin receptor 2 Chain: Y
Molecule details ›
Chain: Y
Length: 189 amino acids
Theoretical weight: 20.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P58335 (Residues: 35-212; Coverage: 39%)
Gene names: ANTXR2, CMG2
Sequence domains: von Willebrand factor type A domain
Structure domains: von Willebrand factor, type A domain

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: P212121
Unit cell:
a: 88.16Å b: 94.118Å c: 135.597Å
α: 90° β: 90° γ: 90°
R R work R free
0.21 0.207 0.266
Expression systems:
  • Bacillus anthracis
  • Escherichia coli BL21(DE3)