X-ray diffraction
1.55Å resolution

Structural Insights and Functional Implications of Choline Acetyltransferase

Source organism: Rattus norvegicus
Entry authors: Govindasamy L, Pedersen B, Lian W, Kukar T, Gu Y, Jin S, Agbandje-McKenna M, Wu D

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Choline O-acetyltransferase Chain: A
Molecule details ›
Chain: A
Length: 639 amino acids
Theoretical weight: 71.91 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
  • Canonical: P32738 (Residues: 2-640; Coverage: 100%)
Gene name: Chat
Sequence domains: Choline/Carnitine o-acyltransferase
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P212121
Unit cell:
a: 138.949Å b: 77.505Å c: 59.209Å
α: 90° β: 90° γ: 90°
R R work R free
0.171 0.171 0.227
Expression system: Escherichia coli