1t10

X-ray diffraction
2.35Å resolution

Phosphoglucose isomerase from Leishmania mexicana in complex with substrate D-fructose-6-phosphate

Released:

Function and Biology Details

Reaction catalysed:
D-glucose 6-phosphate = D-fructose 6-phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glucose-6-phosphate isomerase Chain: A
Molecule details ›
Chain: A
Length: 605 amino acids
Theoretical weight: 67.36 KDa
Source organism: Leishmania mexicana mexicana
Expression system: Escherichia coli
UniProt:
  • Canonical: P42861 (Residues: 1-605; Coverage: 100%)
Gene name: PGI
Sequence domains: Phosphoglucose isomerase
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P6122
Unit cell:
a: 85.129Å b: 85.129Å c: 350.089Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.222 0.22 0.26
Expression system: Escherichia coli